P.D.P UPDATE Osteoporisis
DRUG & THERAPEUTICS UPDATE
02 Dec 2011
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Dear Viewers,
National Institute for Health and Clinical Excellence
NICE has issued final guidance on ranibizumab (Lucentis, Novartis) for the treatment of diabetic macular oedema. It has concluded that the drug does not represent an effective use of NHS resources and has therefore not recommended its use for this condition.
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NICE has published final draft guidance recommending the use of apixaban (Eliquis, Bristol-Myers Squibb and Pfizer) as an option for the prevention of venous thromboembolism in adults who have undergone planned total hip replacement or total knee replacement surgery.
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Medicines and Healthcare products Regulatory Agency
The MHRA has warned that the blood glucose analyser Glucose 201+, manufactured by HemoCue AB, may miss hyperglycaemia if used with outdated software (version 106 or lower). This is of particular concern in neonates.
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The MHRA has launched a learning module on selective serotonin reuptake inhibitors (SSRI) antidepressants for doctors, pharmacists and nurses involved in the care of patients with depression. This self-directed learning package outlines the key risks of this important class of medicines.
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Department of Health
November GP and Practice Team Bulletin published
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Dear Prodigy User
The following PRODIGY topics have been updated to include new evidence and recommendations published by National Institute for Health and Clinical Excellence (NICE), the Driver and Vehicle Licensing Agency (DVLA), and the Medicines and Healthcare products Regulatory Agency (MHRA).
- Alcohol -
problem drinking has been revised to reflect recommendations in the clinical guideline Alcohol-use disorders: diagnosis, assessment and management of harmful drinking and alcohol dependence from NICE (2011).
The prescriptions in Asthma and Chronic obstructive pulmonary disease have been amended to reflect the removal of the black triangle from Serevent Evohaler® (salmeterol cfc-free inhaler).
Bowel screening has been updated to include information on NHS bowel cancer screening programmes in Northern Ireland, Scotland, and Wales.
Breast screening has been updated to include the extension to the age range for women eligible for routine breast screening through the NHS Breast Screening programme in England. The Easy Read patient information leaflet on breast screening has also been updated to reflect these changes.
- Diabetes -
type 1 and Insulin therapy in type 1 diabetes have been updated to include the information on fitness to drive from the DVLA's guidance for medical practitioners, At a glance guide to the current medical standards of fitness to drive (2011).
- Influenza –
seasonal has been revised with the updated doses of oseltamivir in renal impairment in line with the British National Formulary (BNF).
The main changes in Insulin therapy in type 2 diabetes include:
The addition of information on fitness to drive from the DVLA's guidance for medical practitioners, At a glance guide to the current medical standards of fitness to drive (2011).
The removal of Optiset®, Opticlick® and Optipen® devices from the topic as Sanofi are to phase these out by December 2011.
Lipid Modificationhas been updated to include the MHRA warning on the interaction between systemic fusidic acid and statins.
Opioid dependence has been updated to incorporate the relevant recommendations from the NICE guideline Needle and syringe programmes: providing people who inject drugs with injecting equipment (2009) into the topic.
A literature search was conducted in October 2011 to identify evidence-based guidelines, UK policy, systematic reviews, and key RCTs published since the last revision of the following topics:
- Pubic Lice - the literature search identified the United Kingdom National Guideline in the Management of Phthirus pubis infestation (2007) produced by the British Association of Sexual Health and HIV. Recommendations within this guideline are consistent with the current PRODIGY topic therefore no changes to recommendations have been made.
- Roundworm - no changes to clinical recommendations have been made.
- Scabies - the literature search identified the United Kingdom National Guideline on the Management of Scabies infestation (2007) produced by the British Association of Sexual Health and HIV. Recommendations within this guideline are consistent with the current PRODIGY topic therefore no changes to recommendations have been made.
- Threadworm - no changes to clinical recommendations have been made.
Kind Regards
The PRODIGY Team
Round-Up of Clinical Guidance issued during October 2011
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Update on Polycystic Ovary Syndrome
www.pcos.i8.com
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P.D.P UPDATE Osteoporisis
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